I knew, just from casual reading, about Coyote and I was also familiar with Quetzalcoatl. Both of them make an appearance in this book. Out of all the characters, the two that became my favorites were Coyote, known as Chaco, and Fred, a mannegishi (taken from Cree folklore). After I completed the book, I thought back, and came to the conclusion that the characters are really an ensemble. There wasn't one that stood out as being more powerful (relatively speaking) than the others, and there were times when they needed aid from the others when they were in a difficult situation.
Sierra Carter may have been the female main character, but she needed all of the others to be successful in the task that had fallen to her. These others include Kaylee, her friend who practices Vodun, along with Mama Labadie; Rose, the shaman, and Clancy, the security guard/cop at BDSC. I've already mentioned Fred and Chaco. I think all of them felt like they were well developed, and I really liked all of them.
While there were points in the narration where I wasn't quite sure where it was going, I found that by the end, I had really enjoyed this novel. My rating is 4/5 platypires.